CHRONIC KIDNEY DISEASE IN AN ENDEMIC AREA FOR HUMAN AFRICAN TRYPANOSOMIAS (HAT): DOES HAT CONFER LESS SUSCEPTILITY TO KIDNEY DISEASE?

Auteurs : LEPIRA FB, WAMESO MNN, MAKULO JRR, SUMAILI EK, BUKABAU JB, MOKOLI VM, NLANDU YM, NKODILA AN, KAJINGULU FP, ZINGA CV, NSEKA NM.

In Sub-Saharan Africa, APOL1 risk variants that confer protection against Human African Trypanosomiasis (HAT) are associated with increased risk of CKD. We hypothesized that the prevalence of CKD in endemic area for HAT could be lower in HAT infected individuals vs uninfected ones.