Auteurs : Luse JL, Sumaili EK, Mokoli VM, Makulo JRR, Mukendi SK,Masimango MI, Nlandu YM, Nkodila AN, Lepira FB, Mashinda DK, Nseka NM.
Word Congress of Nephrology Cape Town march 13-17, 2015
BACKGROUND:
Twice-weekly hemodialysis (HD) is prevalent in the developing countries including in the DR Congo and the clinical outcome (particular the survival) of this population remains to be elucidated.
METHODS:
In retrospective cohort study, 258 patients ESRD undergoing HD between January 2007 to December 2013 (mean age 53 ± 12 years, 70.4% male, diabetic patients 39%) from two haemodialysis centers, were enrolled. Clinical and HD parameters were used to compare twice or one (N= 144, 56%) -weekly sessions with thrice-weekly (N=114, 44%) HD.
RESULTS:
Compared with patients on thrice-weekly HD, patients undergoing twice-weekly HD were similar age, and had similar longer HD session, but significantly higher spKt/V weekly, and higher proportions of low socioeconomic status (p < 0.001).112 (43%) out of 258 patients studied died. Kaplan-Meier survival analysis indicated that patient survival was better in thrice-weekly HD than in less frequent HD (p = 0.003, figure 1). Multivariate Cox regression analysis showed that low socioeconomic status, serum urea and less frequent (twice or one) weekly HD sessions were independently associated with a significant risk of mortality.
CONCLUSION:
Our findings indicate that twice HD session is prevalent with poor survival related to constraint financials. Hence, increase awareness about CKD, early detection and preventive measures should included in health priority.
Keywords: Haemodialysis, frequency HD sessions, low socioeconomic status, survival
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